A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents

AIM: Glucose-dependent insulinotropic peptide (GIP) is an incretin hormone that is released from intestinal K cells in response to nutrient ingestion. We aimed to investigate the therapeutic potential of the novel N- and C-terminally modified GIP analogue AC163794. METHODS: AC163794 was synthesized...

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Detalles Bibliográficos
Autores principales: Tatarkiewicz, K, Hargrove, D M, Jodka, C M, Gedulin, B R, Smith, P A, Hoyt, J A, Lwin, A, Collins, L, Mamedova, L, Levy, O E, D’Souza, L, Janssen, S, Srivastava, V, Ghosh, S S, Parkes, D G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237114/
https://www.ncbi.nlm.nih.gov/pubmed/23859463
http://dx.doi.org/10.1111/dom.12181

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