Native plasma-derived FVIII/VWF complex has lower sensitivity to FVIII inhibitors than the combination of isolated FVIII and VWF proteins. Impact on Bethesda assay titration of FVIII inhibitors

Sensitivity to FVIII inhibitors of the native plasma-derived (pd) FVIII/VWF complex vs. the complexes formed after exogenous FVIII infusion in the haemophilic patient has not been thoroughly studied. The role of VWF in the interaction of FVIII with inhibitors was studied in vitro using different com...

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Detalles Bibliográficos
Autores principales: Bravo, M I, Da Rocha-Souto, B, Grancha, S, Jorquera, J I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237173/
https://www.ncbi.nlm.nih.gov/pubmed/25156825
http://dx.doi.org/10.1111/hae.12494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237173/
https://www.ncbi.nlm.nih.gov/pubmed/25156825
http://dx.doi.org/10.1111/hae.12494

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