Cargando…

Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe

Glioblastoma multiforme is resistant to conventional anti-tumoral treatments due to its infiltrative nature and capability of relapse; therefore, research efforts focus on characterizing gliomagenesis and identifying molecular targets useful on therapy. New therapeutic strategies are being tested in...

Descripción completa

Detalles Bibliográficos
Autores principales: Cornago, M, Garcia-Alberich, C, Blasco-Angulo, N, Vall-llaura, N, Nager, M, Herreros, J, Comella, J X, Sanchis, D, Llovera, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237242/
https://www.ncbi.nlm.nih.gov/pubmed/25275596
http://dx.doi.org/10.1038/cddis.2014.412