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Latexin sensitizes leukemogenic cells to gamma-irradiation-induced cell-cycle arrest and cell death through Rps3 pathway

Leukemia is a leading cause of cancer death. Recently, the latexin (Lxn) gene was identified as a potential tumor suppressor in several types of solid tumors and lymphoma, and Lxn expression was found to be absent or downregulated in leukemic cells. Whether Lxn functions as a tumor suppressor in leu...

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Detalles Bibliográficos
Autores principales:	You, Y, Wen, R, Pathak, R, Li, A, Li, W, St Clair, D, Hauer-Jensen, M, Zhou, D, Liang, Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237263/ https://www.ncbi.nlm.nih.gov/pubmed/25341047 http://dx.doi.org/10.1038/cddis.2014.443

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