TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival

Nuclear orphan receptor TLX (Drosophila tailless homolog) is essential for the maintenance of neural stem/progenitor cell self-renewal, but its role in neuroblastoma (NB) is not well understood. Here, we show that TLX is essential for the formation of tumor spheres in three different NB cell lines,...

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Detalles Bibliográficos
Autores principales: Chavali, P L, Saini, R K R, Zhai, Q, Vizlin-Hodzic, D, Venkatabalasubramanian, S, Hayashi, A, Johansson, E, Zeng, Z-j, Mohlin, S, Påhlman, S, Hansford, L, Kaplan, D R, Funa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237266/
https://www.ncbi.nlm.nih.gov/pubmed/25356871
http://dx.doi.org/10.1038/cddis.2014.449

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