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Early Chordate Origin of the Vertebrate Integrin αI Domains

Half of the 18 human integrins α subunits have an inserted αI domain yet none have been observed in species that have diverged prior to the appearance of the urochordates (ascidians). The urochordate integrin αI domains are not human orthologues but paralogues, but orthologues of human αI domains ex...

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Detalles Bibliográficos
Autores principales: Chouhan, Bhanupratap Singh, Käpylä, Jarmo, Denessiouk, Konstantin, Denesyuk, Alexander, Heino, Jyrki, Johnson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237329/
https://www.ncbi.nlm.nih.gov/pubmed/25409021
http://dx.doi.org/10.1371/journal.pone.0112064