Comparison of Results from Different Imputation Techniques for Missing Data from an Anti-Obesity Drug Trial

BACKGROUND: In randomised trials of medical interventions, the most reliable analysis follows the intention-to-treat (ITT) principle. However, the ITT analysis requires that missing outcome data have to be imputed. Different imputation techniques may give different results and some may lead to bias....

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Detalles Bibliográficos
Autores principales: Jørgensen, Anders W., Lundstrøm, Lars H., Wetterslev, Jørn, Astrup, Arne, Gøtzsche, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237333/
https://www.ncbi.nlm.nih.gov/pubmed/25409438
http://dx.doi.org/10.1371/journal.pone.0111964

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