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Involvement of IKAP in Peripheral Target Innervation and in Specific JNK and NGF Signaling in Developing PNS Neurons
A splicing mutation in the ikbkap gene causes Familial Dysautonomia (FD), affecting the IKAP protein expression levels and proper development and function of the peripheral nervous system (PNS). Here we attempted to elucidate the role of IKAP in PNS development in the chick embryo and found that IKA...
Autores principales: | Abashidze, Anastasia, Gold, Veronica, Anavi, Yaron, Greenspan, Hayit, Weil, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237409/ https://www.ncbi.nlm.nih.gov/pubmed/25409162 http://dx.doi.org/10.1371/journal.pone.0113428 |
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