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Magnesium Sulfate Treatment Reverses Seizure Susceptibility and Decreases Neuroinflammation in a Rat Model of Severe Preeclampsia
Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO(4)) is the leading eclamptic seizure prophylactic, yet its mechanism of action remains unclear. Here, we hypothesized severe preeclam...
Autores principales: | Johnson, Abbie Chapman, Tremble, Sarah M., Chan, Siu-Lung, Moseley, Janae, LaMarca, Babbette, Nagle, Keith J., Cipolla, Marilyn J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237502/ https://www.ncbi.nlm.nih.gov/pubmed/25409522 http://dx.doi.org/10.1371/journal.pone.0113670 |
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