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Investigational new insulin glargine 300 U/ml has the same metabolism as insulin glargine 100 U/ml
Insulin glargine is processed in vivo into soluble 21(A)-Gly-human insulin (M1), the principal moiety responsible for metabolic effects, and subsequently into M2. This sub-study compared metabolism and metabolite pharmacokinetic (PK) profiles of investigational new insulin glargine U300 (Gla-300) wi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237557/ https://www.ncbi.nlm.nih.gov/pubmed/24571126 http://dx.doi.org/10.1111/dom.12283 |