Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates

Correlating antifungal Azole drug resistance and mis-sense mutations of ERG11 has been paradoxical in pathogenic yeast Candida albicans. Amino acid substitutions (single or multiple) are frequent on ERG11, a membrane bound enzyme of Ergosterol biosynthesis pathway. Presence or absence of mutations c...

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Detalles Bibliográficos
Autores principales: Debnath, Surajit, Addya, Soma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237678/
https://www.ncbi.nlm.nih.gov/pubmed/25512882
http://dx.doi.org/10.1186/2193-1801-3-660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237678/
https://www.ncbi.nlm.nih.gov/pubmed/25512882
http://dx.doi.org/10.1186/2193-1801-3-660

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