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A Multiepitope of XBP1, CD138 and CS1 Peptides Induces Myeloma-Specific Cytotoxic T lymphocytes in T cells of Smoldering Myeloma Patients

We evaluated a cocktail of HLA-A2-specific peptides including heteroclitic XBP1 US(184-192) (YISPWILAV), heteroclitic XBP1 SP(367-375) (YLFPQLISV), native CD138(260-268) (GLVGLIFAV) and native CS1(239-247) (SLFVLGLFL), for their ability to elicit multipeptide specific cytotoxic T lymphocytes (MP-CTL...

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Detalles Bibliográficos
Autores principales: Bae, Jooeun, Prabhala, Rao, Voskertchian, Annie, Brown, Andrew, Maguire, Craig, Richardson, Paul, Dranoff, Glen, Anderson, Kenneth C., Munshi, Nikhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237716/
https://www.ncbi.nlm.nih.gov/pubmed/24935722
http://dx.doi.org/10.1038/leu.2014.159