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Effect of transporter inhibition on the distribution of cefadroxil in rat brain
BACKGROUND: Cefadroxil, a cephalosporin antibiotic, is a substrate for several membrane transporters including peptide transporter 2 (PEPT2), organic anion transporters (OATs), multidrug resistance-associated proteins (MRPs), and organic anion transporting polypeptides (OATPs). These transporters ar...
Autores principales: | Chen, Xiaomei, Loryan, Irena, Payan, Maryam, Keep, Richard F, Smith, David E, Hammarlund-Udenaes, Margareta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237734/ https://www.ncbi.nlm.nih.gov/pubmed/25414790 http://dx.doi.org/10.1186/2045-8118-11-25 |
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