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Hypomethylation and overexpression of ITGAL (CD11a) in CD4(+) T cells in systemic sclerosis
BACKGROUND: The pathogenesis and etiology of systemic sclerosis (SSc) are complex and poorly understood. To date, several studies have demonstrated that the activation of the immune system undoubtedly plays a pivotal role in SSc pathogenesis. Activated immune effector T cells contribute to the relea...
Autores principales: | Wang, YaoYao, Shu, Ye, Xiao, YangFan, Wang, Qing, Kanekura, Takuro, Li, YaPing, Wang, JiuCun, Zhao, Ming, Lu, QianJin, Xiao, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237764/ https://www.ncbi.nlm.nih.gov/pubmed/25414732 http://dx.doi.org/10.1186/1868-7083-6-25 |
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