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Perinatal transmission of dengue: a case report

BACKGROUND: Dengue in pregnancy is associated with many maternal and foetal outcomes including perinatal transmission of dengue infection. CASE PRESENTATION: A baby was born by emergency caesarean section due to foetal distress and meconium stained liquor, to a 27-year old primi-gravidae, Sinhalese...

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Autores principales: Sinhabahu, Vindika Prasad, Sathananthan, Rajeev, Malavige, Gathsaurie Neelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237779/
https://www.ncbi.nlm.nih.gov/pubmed/25394748
http://dx.doi.org/10.1186/1756-0500-7-795
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author Sinhabahu, Vindika Prasad
Sathananthan, Rajeev
Malavige, Gathsaurie Neelika
author_facet Sinhabahu, Vindika Prasad
Sathananthan, Rajeev
Malavige, Gathsaurie Neelika
author_sort Sinhabahu, Vindika Prasad
collection PubMed
description BACKGROUND: Dengue in pregnancy is associated with many maternal and foetal outcomes including perinatal transmission of dengue infection. CASE PRESENTATION: A baby was born by emergency caesarean section due to foetal distress and meconium stained liquor, to a 27-year old primi-gravidae, Sinhalese female, who was febrile during and 2 days prior to labour. The baby had evidence of respiratory distress due to meconium aspiration and was cared for in the special care baby unit for 3 days. On the 4(th) day he developed fever and serial blood counts showed a gradual rise in the haematocrit (>20% of baseline value) and lowering of platelet counts. The baby was treated for sepsis and as Sri Lanka was experiencing a massive dengue epidemic was also tested for dengue. His dengue NS1 antigen test was strongly positive and the dengue IgM antibodies weakly positive on day 3 of illness. The mother was positive for both dengue IgM and IgG antibodies. CONCLUSION: Although rare, vertical transmission of the dengue virus has been reported and the baby most likely developed dengue due to perinatal transmission of dengue.
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spelling pubmed-42377792014-11-21 Perinatal transmission of dengue: a case report Sinhabahu, Vindika Prasad Sathananthan, Rajeev Malavige, Gathsaurie Neelika BMC Res Notes Case Report BACKGROUND: Dengue in pregnancy is associated with many maternal and foetal outcomes including perinatal transmission of dengue infection. CASE PRESENTATION: A baby was born by emergency caesarean section due to foetal distress and meconium stained liquor, to a 27-year old primi-gravidae, Sinhalese female, who was febrile during and 2 days prior to labour. The baby had evidence of respiratory distress due to meconium aspiration and was cared for in the special care baby unit for 3 days. On the 4(th) day he developed fever and serial blood counts showed a gradual rise in the haematocrit (>20% of baseline value) and lowering of platelet counts. The baby was treated for sepsis and as Sri Lanka was experiencing a massive dengue epidemic was also tested for dengue. His dengue NS1 antigen test was strongly positive and the dengue IgM antibodies weakly positive on day 3 of illness. The mother was positive for both dengue IgM and IgG antibodies. CONCLUSION: Although rare, vertical transmission of the dengue virus has been reported and the baby most likely developed dengue due to perinatal transmission of dengue. BioMed Central 2014-11-14 /pmc/articles/PMC4237779/ /pubmed/25394748 http://dx.doi.org/10.1186/1756-0500-7-795 Text en © Sinhabahu et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Sinhabahu, Vindika Prasad
Sathananthan, Rajeev
Malavige, Gathsaurie Neelika
Perinatal transmission of dengue: a case report
title Perinatal transmission of dengue: a case report
title_full Perinatal transmission of dengue: a case report
title_fullStr Perinatal transmission of dengue: a case report
title_full_unstemmed Perinatal transmission of dengue: a case report
title_short Perinatal transmission of dengue: a case report
title_sort perinatal transmission of dengue: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237779/
https://www.ncbi.nlm.nih.gov/pubmed/25394748
http://dx.doi.org/10.1186/1756-0500-7-795
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