Gender dimorphism and age of onset in malignant peripheral nerve sheath tumor preclinical models and human patients

BACKGROUND: Gender-based differences in disease onset in murine models of malignant peripheral nerve sheath tumor (MPNST) and in patients with Neurofibromatosis type-1-(NF-1)-associated or spontaneous MPNST has not been well studied. METHODS: Forty-three mGFAP-Cre+;Pten(loxp/+);LSL-K-ras(G12D/+) mic...

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Detalles Bibliográficos
Autores principales: Shurell, Elizabeth, Tran, Linh M, Nakashima, Jonathan, Smith, Kathleen B, Tam, Brenna M, Li, Yunfeng, Dry, Sarah M, Federman, Noah, Tap, William D, Wu, Hong, Eilber, Fritz C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237782/
https://www.ncbi.nlm.nih.gov/pubmed/25398666
http://dx.doi.org/10.1186/1471-2407-14-827

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