A putative novel protein, DEPDC1B, is overexpressed in oral cancer patients, and enhanced anchorage-independent growth in oral cancer cells that is mediated by Rac1 and ERK

BACKGROUND: The DEP domain is a globular domain containing approximately 90 amino acids, which was first discovered in 3 proteins: Drosophila disheveled, Caenorhabditis elegans EGL-10, and mammalian Pleckstrin; hence the term, DEP. DEPDC1B is categorized as a potential Rho GTPase-activating protein....

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Detalles Bibliográficos
Autores principales: Su, Ying-Fang, Liang, Chi-Yen, Huang, Chih-Yang, Peng, Chih-Yu, Chen, Claire Chiyu, Lin, Ming-Cheng, Lin, Rong-Kai, Lin, Wei-Wen, Chou, Ming-Yung, Liao, Pao-Hsin, Yang, Jaw-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237807/
https://www.ncbi.nlm.nih.gov/pubmed/25091805
http://dx.doi.org/10.1186/s12929-014-0067-1

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