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Activation of caspase-dependent apoptosis by intracellular delivery of cytochrome c-based nanoparticles

BACKGROUND: Cytochrome c is an essential mediator of apoptosis when it is released from the mitochondria to the cytoplasm. This process normally takes place in response to DNA damage, but in many cancer cells (i.e., cancer stem cells) it is disabled due to various mechanisms. However, it has been de...

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Detalles Bibliográficos
Autores principales:	Morales-Cruz, Moraima, Figueroa, Cindy M, González-Robles, Tania, Delgado, Yamixa, Molina, Anna, Méndez, Jessica, Morales, Myraida, Griebenow, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237869/ https://www.ncbi.nlm.nih.gov/pubmed/25179308 http://dx.doi.org/10.1186/s12951-014-0033-9

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