Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule

BACKGROUND: Fragile X Syndrome (FXS) is the most common form of inherited intellectual disability and is also associated with autism spectrum disorders. Previous studies implicated BKCa channels in the neuropathogenesis of FXS, but the main question was whether pharmacological BKCa stimulation would...

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Detalles Bibliográficos
Autores principales: Hébert, Betty, Pietropaolo, Susanna, Même, Sandra, Laudier, Béatrice, Laugeray, Anthony, Doisne, Nicolas, Quartier, Angélique, Lefeuvre, Sandrine, Got, Laurence, Cahard, Dominique, Laumonnier, Frédéric, Crusio, Wim E, Pichon, Jacques, Menuet, Arnaud, Perche, Olivier, Briault, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237919/
https://www.ncbi.nlm.nih.gov/pubmed/25079250
http://dx.doi.org/10.1186/s13023-014-0124-6

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