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Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

BACKGROUND: The 5XFAD early onset mouse model of Alzheimer’s disease (AD) is gaining momentum. Behavioral, electrophysiological and anatomical studies have identified age-dependent alterations that can be reminiscent of human AD. However, transcriptional changes during disease progression have not y...

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Detalles Bibliográficos
Autores principales:	Landel, Véréna, Baranger, Kévin, Virard, Isabelle, Loriod, Béatrice, Khrestchatisky, Michel, Rivera, Santiago, Benech, Philippe, Féron, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237952/ https://www.ncbi.nlm.nih.gov/pubmed/25213090 http://dx.doi.org/10.1186/1750-1326-9-33

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