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Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors

BACKGROUND: Histamine (HA) regulates the sleep-wake cycle, synaptic plasticity and memory in adult mammals. Dopaminergic specification in the embryonic ventral midbrain (VM) coincides with increased HA brain levels. To study the effect of HA receptor stimulation on dopamine neuron generation, we adm...

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Detalles Bibliográficos
Autores principales:	Escobedo-Avila, Itzel, Vargas-Romero, Fernanda, Molina-Hernández, Anayansi, López-González, Rodrigo, Cortés, Daniel, De Carlos, Juan A, Velasco, Iván
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237960/ https://www.ncbi.nlm.nih.gov/pubmed/25112718 http://dx.doi.org/10.1186/s13041-014-0058-x

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