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Adenosine monophosphate-activated protein kinase activation enhances embryonic neural stem cell apoptosis in a mouse model of amyotrophic lateral sclerosis

Alterations in embryonic neural stem cells play crucial roles in the pathogenesis of amyotrophic lateral sclerosis. We hypothesized that embryonic neural stem cells from SOD1(G93A) individuals might be more susceptible to oxidative injury, resulting in a propensity for neurodegeneration at later sta...

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Detalles Bibliográficos
Autores principales: Sui, Yanling, Zhao, Zichun, Liu, Rong, Cai, Bin, Fan, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238165/
https://www.ncbi.nlm.nih.gov/pubmed/25422638
http://dx.doi.org/10.4103/1673-5374.143421

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