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MicroRNA-mediated regulation of extracellular matrix formation modulates somatic cell reprogramming

Somatic cells can be reprogrammed to reach an embryonic stem cell-like state by overexpression of defined factors. Recent studies have greatly improved the efficiency of the reprogramming process but the underlying mechanisms regulating the transition from a somatic to a pluripotent state are still...

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Detalles Bibliográficos
Autores principales: Li, Zhonghan, Dang, Jason, Chang, Kung-Yen, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238355/
https://www.ncbi.nlm.nih.gov/pubmed/25336587
http://dx.doi.org/10.1261/rna.043745.113

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