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Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness

Titin-based myofilament stiffness is largely modulated by phosphorylation of its elastic I-band regions N2-Bus (decreases passive stiffness, PT) and PEVK (increases PT). Here, we tested the hypothesis that acute exercise changes titin phosphorylation and modifies myofilament stiffness. Adult rats we...

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Detalles Bibliográficos
Autores principales:	Müller, Anna E., Kreiner, Matthias, Kötter, Sebastian, Lassak, Philipp, Bloch, Wilhelm, Suhr, Frank, Krüger, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238368/ https://www.ncbi.nlm.nih.gov/pubmed/25477822 http://dx.doi.org/10.3389/fphys.2014.00449

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