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Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry for Top-Down Characterization of Pyrococcus furiosus Proteins on a Proteome Scale
[Image: see text] Intact protein analysis via top-down mass spectrometry (MS) provides the unique capability of fully characterizing protein isoforms and combinatorial post-translational modifications (PTMs) compared to the bottom-up MS approach. Front-end protein separation poses a challenge for an...
Autores principales: | Han, Xuemei, Wang, Yueju, Aslanian, Aaron, Bern, Marshall, Lavallée-Adam, Mathieu, Yates, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238646/ https://www.ncbi.nlm.nih.gov/pubmed/25346219 http://dx.doi.org/10.1021/ac503439n |
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