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Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells

Heat shock protein 90 (Hsp90) is constitutively expressed at 2-10-fold higher levels in tumor cells compared to normal cells, suggesting that it may be critically important for tumor cell growth and survival. These features make Hsp90 a potential target for anticancer drug development. Inhibition of...

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Detalles Bibliográficos
Autores principales:	MORI, MASAKI, HITORA, TOSHIAKI, NAKAMURA, OSAMU, YAMAGAMI, YOSHIKI, HORIE, RYOSUKE, NISHIMURA, HIDEKI, YAMAMOTO, TETSUJI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238730/ https://www.ncbi.nlm.nih.gov/pubmed/25351442 http://dx.doi.org/10.3892/ijo.2014.2727

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