Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug

OBJECTIVES: The single- and multiple-dose pharmacokinetics (PK) of tedizolid were examined after oral administration of tedizolid phosphate disodium (TPD), including the effect of food on PK. The relative bioavailability of TPD to the free acid tedizolid phosphate was determined to bridge the result...

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Detalles Bibliográficos
Autores principales: Flanagan, Shawn D, Bien, Paul A, Muñoz, Kelly A, Minassian, Sonia L, Prokocimer, Philippe G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238735/
https://www.ncbi.nlm.nih.gov/pubmed/23926058
http://dx.doi.org/10.1002/phar.1337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238735/
https://www.ncbi.nlm.nih.gov/pubmed/23926058
http://dx.doi.org/10.1002/phar.1337

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