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Pharmacokinetics of Tedizolid Following Oral Administration: Single and Multiple Dose, Effect of Food, and Comparison of Two Solid Forms of the Prodrug
OBJECTIVES: The single- and multiple-dose pharmacokinetics (PK) of tedizolid were examined after oral administration of tedizolid phosphate disodium (TPD), including the effect of food on PK. The relative bioavailability of TPD to the free acid tedizolid phosphate was determined to bridge the result...
Autores principales: | Flanagan, Shawn D, Bien, Paul A, Muñoz, Kelly A, Minassian, Sonia L, Prokocimer, Philippe G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238735/ https://www.ncbi.nlm.nih.gov/pubmed/23926058 http://dx.doi.org/10.1002/phar.1337 |
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