Inactivation of chromatin remodeling factors sensitizes cells to selective cytotoxic stress

The SWI/SNF chromatin-remodeling complex plays an essential role in several cellular processes including cell proliferation, differentiation, and DNA repair. Loss of normal function of the SWI/SNF complex because of mutations in its subunits correlates with tumorigenesis in humans. For many of these...

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Detalles Bibliográficos
Autores principales: Freeman, Miles D, Mazu, Tryphon, Miles, Jana S, Darling-Reed, Selina, Flores-Rozas, Hernan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238754/
https://www.ncbi.nlm.nih.gov/pubmed/25484574
http://dx.doi.org/10.2147/BTT.S67046

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