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Ophthalmological Features of Parkinson Disease

BACKGROUND: The aim of this study was to determine the type and frequency of ophthalmologic changes occurring in patients with Parkinson disease (PD). MATERIAL/METHODS: One hundred consecutive patients (196 eyes) with idiopathic PD and a control group consisting of 100 healthy patients (196 eyes) ma...

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Autores principales: Nowacka, Barbara, Lubiński, Wojciech, Honczarenko, Krystyna, Potemkowski, Andrzej, Safranow, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238794/
https://www.ncbi.nlm.nih.gov/pubmed/25387009
http://dx.doi.org/10.12659/MSM.890861
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author Nowacka, Barbara
Lubiński, Wojciech
Honczarenko, Krystyna
Potemkowski, Andrzej
Safranow, Krzysztof
author_facet Nowacka, Barbara
Lubiński, Wojciech
Honczarenko, Krystyna
Potemkowski, Andrzej
Safranow, Krzysztof
author_sort Nowacka, Barbara
collection PubMed
description BACKGROUND: The aim of this study was to determine the type and frequency of ophthalmologic changes occurring in patients with Parkinson disease (PD). MATERIAL/METHODS: One hundred consecutive patients (196 eyes) with idiopathic PD and a control group consisting of 100 healthy patients (196 eyes) matched for age and sex underwent a complete ophthalmological examination of both eyes, including assessment of patient medical history, dry eye questionare, and visual hallucinations questionnaire, distance and near best corrected visual acuity (DBCVA, NBCVA), color vision, distance photopic contrast sensitivity, near point of convergence, slit lamp examination of the eye anterior segment, tear film osmolarity and breakup time, aqueous tear production, and intraocular pressure, as well as fundus examination and evaluation of the perimacular retinal thickness (RT) and peripapillary retinal nerve fiber layer (RNFL) thickness. RESULTS: In the eyes of PD patients DBCVA, NBCVA, contrast sensitivity, and color discrimination were significantly reduced. We also detected increased frequency of convergence insufficiency, seborrhoic blepharitis, meibomian gland disease (MGD), dry eye syndrome, nuclear and posterior subcapsular cataract, and glaucoma (p<0.05). However, intraocular pressure (IOP) was significantly lower in the PD group compared to controls. The frequency of visual hallucinations, age-related macular degeneration (ARMD), and other ophthalmological diseases, as well as RT and RNFL thickness, did not significantly differ between investigated groups. CONCLUSIONS: Clinicians need to be aware of the association between PD and ophthalmological changes. Restoration of good-quality vision has a great impact on PD patients’ quality of life, reduction of costs of treatment and care, and rehabilitation.
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spelling pubmed-42387942014-11-21 Ophthalmological Features of Parkinson Disease Nowacka, Barbara Lubiński, Wojciech Honczarenko, Krystyna Potemkowski, Andrzej Safranow, Krzysztof Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to determine the type and frequency of ophthalmologic changes occurring in patients with Parkinson disease (PD). MATERIAL/METHODS: One hundred consecutive patients (196 eyes) with idiopathic PD and a control group consisting of 100 healthy patients (196 eyes) matched for age and sex underwent a complete ophthalmological examination of both eyes, including assessment of patient medical history, dry eye questionare, and visual hallucinations questionnaire, distance and near best corrected visual acuity (DBCVA, NBCVA), color vision, distance photopic contrast sensitivity, near point of convergence, slit lamp examination of the eye anterior segment, tear film osmolarity and breakup time, aqueous tear production, and intraocular pressure, as well as fundus examination and evaluation of the perimacular retinal thickness (RT) and peripapillary retinal nerve fiber layer (RNFL) thickness. RESULTS: In the eyes of PD patients DBCVA, NBCVA, contrast sensitivity, and color discrimination were significantly reduced. We also detected increased frequency of convergence insufficiency, seborrhoic blepharitis, meibomian gland disease (MGD), dry eye syndrome, nuclear and posterior subcapsular cataract, and glaucoma (p<0.05). However, intraocular pressure (IOP) was significantly lower in the PD group compared to controls. The frequency of visual hallucinations, age-related macular degeneration (ARMD), and other ophthalmological diseases, as well as RT and RNFL thickness, did not significantly differ between investigated groups. CONCLUSIONS: Clinicians need to be aware of the association between PD and ophthalmological changes. Restoration of good-quality vision has a great impact on PD patients’ quality of life, reduction of costs of treatment and care, and rehabilitation. International Scientific Literature, Inc. 2014-11-11 /pmc/articles/PMC4238794/ /pubmed/25387009 http://dx.doi.org/10.12659/MSM.890861 Text en © Med Sci Monit, 2014 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License
spellingShingle Clinical Research
Nowacka, Barbara
Lubiński, Wojciech
Honczarenko, Krystyna
Potemkowski, Andrzej
Safranow, Krzysztof
Ophthalmological Features of Parkinson Disease
title Ophthalmological Features of Parkinson Disease
title_full Ophthalmological Features of Parkinson Disease
title_fullStr Ophthalmological Features of Parkinson Disease
title_full_unstemmed Ophthalmological Features of Parkinson Disease
title_short Ophthalmological Features of Parkinson Disease
title_sort ophthalmological features of parkinson disease
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238794/
https://www.ncbi.nlm.nih.gov/pubmed/25387009
http://dx.doi.org/10.12659/MSM.890861
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