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A Systems Genetics Approach Identifies CXCL14, ITGAX, and LPCAT2 as Novel Aggressive Prostate Cancer Susceptibility Genes
Although prostate cancer typically runs an indolent course, a subset of men develop aggressive, fatal forms of this disease. We hypothesize that germline variation modulates susceptibility to aggressive prostate cancer. The goal of this work is to identify susceptibility genes using the C57BL/6-Tg(T...
Autores principales: | Williams, Kendra A., Lee, Minnkyong, Hu, Ying, Andreas, Jonathan, Patel, Shashank J., Zhang, Suiyuan, Chines, Peter, Elkahloun, Abdel, Chandrasekharappa, Settara, Gutkind, J. Silvio, Molinolo, Alfredo A., Crawford, Nigel P. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238980/ https://www.ncbi.nlm.nih.gov/pubmed/25411967 http://dx.doi.org/10.1371/journal.pgen.1004809 |
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