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Metabolic Profiling and Flux Analysis of MEL-2 Human Embryonic Stem Cells during Exponential Growth at Physiological and Atmospheric Oxygen Concentrations

As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine applications there is an increasing emphasis on the development of bioreactor platforms that enable expansion of these cells to clinically relevant numbers. Surprisingly little is known about the metabolic requirem...

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Detalles Bibliográficos
Autores principales: Turner, Jennifer, Quek, Lake-Ee, Titmarsh, Drew, Krömer, Jens O., Kao, Li-Pin, Nielsen, Lars, Wolvetang, Ernst, Cooper-White, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239018/
https://www.ncbi.nlm.nih.gov/pubmed/25412279
http://dx.doi.org/10.1371/journal.pone.0112757