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Metabolic Profiling and Flux Analysis of MEL-2 Human Embryonic Stem Cells during Exponential Growth at Physiological and Atmospheric Oxygen Concentrations
As human embryonic stem cells (hESCs) steadily progress towards regenerative medicine applications there is an increasing emphasis on the development of bioreactor platforms that enable expansion of these cells to clinically relevant numbers. Surprisingly little is known about the metabolic requirem...
Autores principales: | Turner, Jennifer, Quek, Lake-Ee, Titmarsh, Drew, Krömer, Jens O., Kao, Li-Pin, Nielsen, Lars, Wolvetang, Ernst, Cooper-White, Justin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239018/ https://www.ncbi.nlm.nih.gov/pubmed/25412279 http://dx.doi.org/10.1371/journal.pone.0112757 |
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