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Inactivation of SAM-Methyltransferase is the Mechanism of Attenuation of a Historic Louse Borne Typhus Vaccine Strain

Louse borne typhus (also called epidemic typhus) was one of man's major scourges, and epidemics of the disease can be reignited when social, economic, or political systems are disrupted. The fear of a bioterrorist attack using the etiologic agent of typhus, Rickettsia prowazekii, was a reality....

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Detalles Bibliográficos
Autores principales: Liu, Yan, Wu, Bin, Weinstock, George, Walker, David H., Yu, Xue-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239044/
https://www.ncbi.nlm.nih.gov/pubmed/25412248
http://dx.doi.org/10.1371/journal.pone.0113285

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