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Early Growth Response 4 Is Involved in Cell Proliferation of Small Cell Lung Cancer through Transcriptional Activation of Its Downstream Genes

Small cell lung cancer (SCLC) is aggressive, with rapid growth and frequent bone metastasis; however, its detailed molecular mechanism remains poorly understood. Here, we report the critical role of early growth factor 4 (EGR4), a DNA-binding, zinc-finger transcription factor, in cell proliferation...

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Detalles Bibliográficos
Autores principales: Matsuo, Taisuke, Dat, Le Tan, Komatsu, Masato, Yoshimaru, Tetsuro, Daizumoto, Kei, Sone, Saburo, Nishioka, Yasuhiko, Katagiri, Toyomasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239076/
https://www.ncbi.nlm.nih.gov/pubmed/25411851
http://dx.doi.org/10.1371/journal.pone.0113606

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