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Microbial Contamination in Next Generation Sequencing: Implications for Sequence-Based Analysis of Clinical Samples

The high level of accuracy and sensitivity of next generation sequencing for quantifying genetic material across organismal boundaries gives it tremendous potential for pathogen discovery and diagnosis in human disease. Despite this promise, substantial bacterial contamination is routinely found in...

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Detalles Bibliográficos
Autores principales:	Strong, Michael J., Xu, Guorong, Morici, Lisa, Splinter Bon-Durant, Sandra, Baddoo, Melody, Lin, Zhen, Fewell, Claire, Taylor, Christopher M., Flemington, Erik K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239086/ https://www.ncbi.nlm.nih.gov/pubmed/25412476 http://dx.doi.org/10.1371/journal.ppat.1004437

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