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Cdk5/p35 functions as a crucial regulator of spatial learning and memory

BACKGROUND: Cyclin-dependent kinase 5 (Cdk5), which is activated by binding to p35 or p39, is involved in synaptic plasticity and affects learning and memory formation. In Cdk5 knockout (KO) mice and p35 KO mice, brain development is severely impaired because neuronal migration is impaired and lamin...

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Detalles Bibliográficos
Autores principales:	Mishiba, Tomohide, Tanaka, Mika, Mita, Naoki, He, Xiaojuan, Sasamoto, Kodai, Itohara, Shigeyoshi, Ohshima, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239319/ https://www.ncbi.nlm.nih.gov/pubmed/25404232 http://dx.doi.org/10.1186/s13041-014-0082-x

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