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High-fat diet-induced changes in liver thioredoxin and thioredoxin reductase as a novel feature of insulin resistance
High-fat diet (HFD) can induce oxidative stress. Thioredoxin (Trx) and thioredoxin reductase (TrxR) are critical antioxidant proteins but how they are affected by HFD remains unclear. Using HFD-induced insulin-resistant mouse model, we show here that liver Trx and TrxR are significantly decreased, b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239481/ https://www.ncbi.nlm.nih.gov/pubmed/25426412 http://dx.doi.org/10.1016/j.fob.2014.10.015 |