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Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1
Caspase-11 is a highly inducible caspase that controls both inflammatory responses and cell death. Caspase-11 controls interleukin 1β (IL-1β) secretion by potentiating caspase-1 activation and induces caspase-1-independent pyroptosis downstream of noncanonical NLRP3 inflammasome activators such as l...
Autores principales: | Py, Bénédicte F., Jin, Mingzhi, Desai, Bimal N., Penumaka, Anirudh, Zhu, Hong, Kober, Maike, Dietrich, Alexander, Lipinski, Marta M., Henry, Thomas, Clapham, David E., Yuan, Junying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239700/ https://www.ncbi.nlm.nih.gov/pubmed/24630989 http://dx.doi.org/10.1016/j.celrep.2014.02.015 |
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