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Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

Caspase-11 is a highly inducible caspase that controls both inflammatory responses and cell death. Caspase-11 controls interleukin 1β (IL-1β) secretion by potentiating caspase-1 activation and induces caspase-1-independent pyroptosis downstream of noncanonical NLRP3 inflammasome activators such as l...

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Detalles Bibliográficos
Autores principales: Py, Bénédicte F., Jin, Mingzhi, Desai, Bimal N., Penumaka, Anirudh, Zhu, Hong, Kober, Maike, Dietrich, Alexander, Lipinski, Marta M., Henry, Thomas, Clapham, David E., Yuan, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239700/
https://www.ncbi.nlm.nih.gov/pubmed/24630989
http://dx.doi.org/10.1016/j.celrep.2014.02.015

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