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Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4(fky/fky) mouse

Mitochondrial dysfunction causes a range of early-onset neurological diseases and contributes to neurodegenerative conditions. The mechanisms of neurological damage however are poorly understood, as accessing relevant tissue from patients is difficult, and appropriate models are limited. Hence, we a...

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Detalles Bibliográficos
Autores principales: Bird, Matthew J., Wijeyeratne, Xiaonan W., Komen, Jasper C., Laskowski, Adrienne, Ryan, Michael T., Thorburn, David R., Frazier, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240023/
https://www.ncbi.nlm.nih.gov/pubmed/25312000
http://dx.doi.org/10.1042/BSR20140151