TCF7L2 is a master regulator of insulin production and processing

Genome-wide association studies have revealed >60 loci associated with type 2 diabetes (T2D), but the underlying causal variants and functional mechanisms remain largely elusive. Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on islet functi...

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Detalles Bibliográficos
Autores principales: Zhou, Yuedan, Park, Soo-Young, Su, Jing, Bailey, Kathleen, Ottosson-Laakso, Emilia, Shcherbina, Liliya, Oskolkov, Nikolay, Zhang, Enming, Thevenin, Thomas, Fadista, João, Bennet, Hedvig, Vikman, Petter, Wierup, Nils, Fex, Malin, Rung, Johan, Wollheim, Claes, Nobrega, Marcelo, Renström, Erik, Groop, Leif, Hansson, Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240194/
https://www.ncbi.nlm.nih.gov/pubmed/25015099
http://dx.doi.org/10.1093/hmg/ddu359

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