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Bone-Targeted Acid-Sensitive Doxorubicin Conjugate Micelles as Potential Osteosarcoma Therapeutics

[Image: see text] Osteosarcoma is a malignancy of the bone that primarily affects adolescents. Current treatments retain mortality rates, which are higher than average cancer mortality rates for the adolescent age group. We designed a micellar delivery system with the aim to increase drug accumulati...

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Detalles Bibliográficos
Autores principales: Low, Stewart A., Yang, Jiyuan, Kopeček, Jindřich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240342/
https://www.ncbi.nlm.nih.gov/pubmed/25291150
http://dx.doi.org/10.1021/bc500392x