Cargando…

FITC-Conjugated Cyclic RGD Peptides as Fluorescent Probes for Staining Integrin α(v)β(3)/α(v)β(5) in Tumor Tissues

[Image: see text] This study sought to evaluate FITC-conjugated cyclic RGD peptides (FITC-RGD(2), FITC-3P-RGD(2), and FITC-Galacto-RGD(2)) as fluorescent probes for in vitro assays of integrin α(v)β(3)/α(v)β(5) expression in tumor tissues. FITC-RGD(2), FITC-3P-RGD(2), and FITC-Galacto-RGD(2) were pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Yumin, Ji, Shundong, Czerwinski, Andrzej, Valenzuela, Francisco, Pennington, Michael, Liu, Shuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240344/ https://www.ncbi.nlm.nih.gov/pubmed/25312799 http://dx.doi.org/10.1021/bc500452y

Ejemplares similares

Integrin α(v)β(3)-Targeted Radiotracer (99m)Tc-3P-RGD(2) Useful for Noninvasive Monitoring of Breast Tumor Response to Antiangiogenic Linifanib Therapy but not Anti-Integrin α(v)β(3) RGD(2) Therapy
por: Ji, Shundong, et al.
Publicado: (2013)

Multivalency Increases the Binding Strength of RGD Peptidomimetic‐Paclitaxel Conjugates to Integrin α(V)β(3)
por: Raposo Moreira Dias, André, et al.
Publicado: (2017)

Investigating the Interaction of Cyclic RGD Peptidomimetics with α(V)β(6) Integrin by Biochemical and Molecular Docking Studies
por: Civera, Monica, et al.
Publicado: (2017)

Comparison of cyclic RGD peptides for α(v)β(3) integrin detection in a rat model of myocardial infarction
por: Laitinen, Iina, et al.
Publicado: (2013)

Comparison of Linear vs. Cyclic RGD Pentapeptide Interactions with Integrin α(v)β(3) by Molecular Dynamics Simulations
por: Li, Na, et al.
Publicado: (2021)

The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection
por: Bieri, Manuela, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of RGD and isoDGR–Monomethyl Auristatin Conjugates Targeting Integrin α(V)β(3)
por: Raposo Moreira Dias, André, et al.
Publicado: (2019)

PET Diagnostic Molecules Utilizing Multimeric Cyclic RGD Peptide Analogs for Imaging Integrin α(v)β(3) Receptors
por: Liolios, Christos, et al.
Publicado: (2021)

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin α(v)β(3)
por: Chen, Haojun, et al.
Publicado: (2016)

A cyclic-RGD-BioShuttle functionalized with TMZ by DAR(inv) “Click Chemistry” targeted to α(v)β(3) integrin for therapy
por: Braun, Klaus, et al.
Publicado: (2010)

Structure–Activity Relationship of RGD-Containing Cyclic Octapeptide and αvβ3 Integrin Allows for Rapid Identification of a New Peptide Antagonist
por: Silva, Aaron, et al.
Publicado: (2020)

Structure–Activity Relationships of RGD-Containing Peptides in Integrin αvβ5-Mediated Cell Adhesion
por: Yamada, Yuji, et al.
Publicado: (2023)

Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a Dimeric-cRGD Peptide for Targeted Imaging of α(V)β(3) Integrin Activity
por: Hedhli, Jamila, et al.
Publicado: (2017)

Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies
por: Guzzetti, Ileana, et al.
Publicado: (2016)

There is a world beyond αvβ3-integrin: Multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography
por: Steiger, Katja, et al.
Publicado: (2021)

Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin
por: Quigley, Neil Gerard, et al.
Publicado: (2020)

A selective cyclic integrin antagonist blocks the integrin receptors α(v)β(3 )and α(v)β(5 )and inhibits retinal pigment epithelium cell attachment, migration and invasion
por: Hoffmann, Stephan, et al.
Publicado: (2005)

RGD-avidin–biotin pretargeting to α(v)β(3) integrin enhances the proapoptotic activity of TNFα related apoptosis inducing ligand (TRAIL)
por: Tarrus, Marc, et al.
Publicado: (2007)

In vivo optical imaging of integrin α(V)-β(3 )in mice using multivalent or monovalent cRGD targeting vectors
por: Jin, Zhao-Hui, et al.
Publicado: (2007)

(68)Ga-BBN-RGD PET/CT for GRPR and Integrin α(v)β(3) Imaging in Patients with Breast Cancer
por: Zhang, Jingjing, et al.
Publicado: (2018)

RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating α(v)β(3) expression
por: Xu, Wencai, et al.
Publicado: (2012)

Side chain effect in the modulation of α(v)β(3)/α(5)β(1) integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems
por: Ferrazzano, Lucia, et al.
Publicado: (2020)

Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression
por: Quaglia, Fabio, et al.
Publicado: (2021)

A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8
por: Le, Viet Q., et al.
Publicado: (2023)

Palmitic Acid-Conjugated Radiopharmaceutical for Integrin α(v)β(3)-Targeted Radionuclide Therapy
por: Yang, Guangjie, et al.
Publicado: (2022)

Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [(18)F]Galacto-RGD
por: Haubner, Roland, et al.
Publicado: (2005)

PET imaging of α(v)β(3) integrin expression in tumours with (68)Ga-labelled mono-, di- and tetrameric RGD peptides
por: Dijkgraaf, Ingrid, et al.
Publicado: (2010)

Recombinant RGD-disintegrin DisBa-01 blocks integrin α(v)β(3) and impairs VEGF signaling in endothelial cells
por: Danilucci, Taís M., et al.
Publicado: (2019)

Imaging of α(v)β(3) integrin expression in experimental myocardial ischemia with [(68)Ga]NODAGA-RGD positron emission tomography
por: Grönman, Maria, et al.
Publicado: (2017)

Biological Production of an Integrin αvβ3 Targeting Imaging Probe and Functional Verification
por: Hwang, Mi-Hye, et al.
Publicado: (2015)

Integrins α(v)β(3) and α(v)β(5) as prognostic, diagnostic, and therapeutic targets in gastric cancer
por: Böger, Christine, et al.
Publicado: (2014)

Epitopes in α8β1 and other RGD-binding integrins delineate classes of integrin-blocking antibodies and major binding loops in α subunits
por: Nishimichi, Norihisa, et al.
Publicado: (2015)

Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition
por: Chang, Yao-Tsung, et al.
Publicado: (2017)

Antitumor activity of integrin α(V)β(3) antibody conjugated-cationic microbubbles in liver cancer
por: Li, Jiale, et al.
Publicado: (2019)

TGFβ(1 )signaling via α(V)β(6 )integrin
por: Kracklauer, Martin P, et al.
Publicado: (2003)

(18)F-FP-PEG(2)-β-Glu-RGD(2): A Symmetric Integrin α(v)β(3)-Targeting Radiotracer for Tumor PET Imaging
por: Hu, Kongzhen, et al.
Publicado: (2015)

Clinical Evaluation of (68)Ga-FAPI-RGD for Imaging of Fibroblast Activation Protein and Integrin α(v)β(3) in Various Cancer Types
por: Zhao, Liang, et al.
Publicado: (2023)

αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation
por: Benito-Jardón, María, et al.
Publicado: (2020)

Expression of α(v)β(6)integrin in oral leukoplakia
por: Hamidi, S, et al.
Publicado: (2000)

PET Imaging of Integrin αVβ3 Expression
por: Beer, Ambros J., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_donrc16ime18i51odtsrjkb4d1