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Solution Structure of the SGTA Dimerisation Domain and Investigation of Its Interactions with the Ubiquitin-Like Domains of BAG6 and UBL4A

BACKGROUND: The BAG6 complex resides in the cytosol and acts as a sorting point to target diverse hydrophobic protein substrates along their appropriate paths, including proteasomal degradation and ER membrane insertion. Composed of a trimeric complex of BAG6, TRC35 and UBL4A, the BAG6 complex is cl...

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Detalles Bibliográficos
Autores principales: Darby, John F., Krysztofinska, Ewelina M., Simpson, Peter J., Simon, Aline C., Leznicki, Pawel, Sriskandarajah, Newran, Bishop, David S., Hale, Lisa R., Alfano, Caterina, Conte, Maria R., Martínez-Lumbreras, Santiago, Thapaliya, Arjun, High, Stephen, Isaacson, Rivka L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240585/
https://www.ncbi.nlm.nih.gov/pubmed/25415308
http://dx.doi.org/10.1371/journal.pone.0113281