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Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007
The Mombasa Cohort is an open cohort study following HIV-seronegative women reporting transactional sex. Established in 1993, the cohort provides regular HIV counseling and testing at monthly visits. Over time, HIV acquisition risk has declined steadily in this cohort. To evaluate whether this decli...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240588/ https://www.ncbi.nlm.nih.gov/pubmed/25415287 http://dx.doi.org/10.1371/journal.pone.0113543 |
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author | Graham, Susan M. Raboud, Janet Jaoko, Walter Mandaliya, Kishor McClelland, R. Scott Bayoumi, Ahmed M. |
author_facet | Graham, Susan M. Raboud, Janet Jaoko, Walter Mandaliya, Kishor McClelland, R. Scott Bayoumi, Ahmed M. |
author_sort | Graham, Susan M. |
collection | PubMed |
description | The Mombasa Cohort is an open cohort study following HIV-seronegative women reporting transactional sex. Established in 1993, the cohort provides regular HIV counseling and testing at monthly visits. Over time, HIV acquisition risk has declined steadily in this cohort. To evaluate whether this decline may reflect changes in sexual risk behavior, we investigated trends in condom use and partner numbers among women who participated in the Mombasa Cohort between 1993 and 2007. Multinomial logistic regression and generalized estimating equations were used to evaluate the association of calendar time and follow-up time with key risk behaviors, after adjustment for potential confounding factors. At enrollment visits by 1,844 women, the adjusted probability of never using condoms decreased over time, from 34.2% to 18.9%. Over 23,911 follow-up visits, the adjusted probabilities of reporting >2 partners decreased from 9.9% to 4.9% and inconsistent condom use decreased from 7.9% to 5.3% after ≥12 cohort visits. Important predictors of risk behavior were work venue, charging low fees for sex, and substance abuse. Women with a later sexual debut had less risky behavior. Although sexual risk has declined among women participating in the Mombasa Cohort, HIV acquisition continues to occur and interventions to promote and reinforce safer sex are clearly needed. |
format | Online Article Text |
id | pubmed-4240588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-42405882014-11-26 Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 Graham, Susan M. Raboud, Janet Jaoko, Walter Mandaliya, Kishor McClelland, R. Scott Bayoumi, Ahmed M. PLoS One Research Article The Mombasa Cohort is an open cohort study following HIV-seronegative women reporting transactional sex. Established in 1993, the cohort provides regular HIV counseling and testing at monthly visits. Over time, HIV acquisition risk has declined steadily in this cohort. To evaluate whether this decline may reflect changes in sexual risk behavior, we investigated trends in condom use and partner numbers among women who participated in the Mombasa Cohort between 1993 and 2007. Multinomial logistic regression and generalized estimating equations were used to evaluate the association of calendar time and follow-up time with key risk behaviors, after adjustment for potential confounding factors. At enrollment visits by 1,844 women, the adjusted probability of never using condoms decreased over time, from 34.2% to 18.9%. Over 23,911 follow-up visits, the adjusted probabilities of reporting >2 partners decreased from 9.9% to 4.9% and inconsistent condom use decreased from 7.9% to 5.3% after ≥12 cohort visits. Important predictors of risk behavior were work venue, charging low fees for sex, and substance abuse. Women with a later sexual debut had less risky behavior. Although sexual risk has declined among women participating in the Mombasa Cohort, HIV acquisition continues to occur and interventions to promote and reinforce safer sex are clearly needed. Public Library of Science 2014-11-21 /pmc/articles/PMC4240588/ /pubmed/25415287 http://dx.doi.org/10.1371/journal.pone.0113543 Text en © 2014 Graham et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Graham, Susan M. Raboud, Janet Jaoko, Walter Mandaliya, Kishor McClelland, R. Scott Bayoumi, Ahmed M. Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title | Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title_full | Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title_fullStr | Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title_full_unstemmed | Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title_short | Changes in Sexual Risk Behavior in the Mombasa Cohort: 1993–2007 |
title_sort | changes in sexual risk behavior in the mombasa cohort: 1993–2007 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240588/ https://www.ncbi.nlm.nih.gov/pubmed/25415287 http://dx.doi.org/10.1371/journal.pone.0113543 |
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