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Heterologous Expression of Equine CYP3A94 and Investigation of a Tunable System to Regulate Co-Expressed NADPH P450 Oxidoreductase Levels

The activity of cytochrome P450 enzymes depends on the enzyme NADPH P450 oxidoreductase (POR). The aim of this study was to investigate the activity of the equine CYP3A94 using a system that allows to regulate the POR protein levels in mammalian cells. CYP3A94 and the equine POR were heterologously...

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Detalles Bibliográficos
Autores principales:	Dettwiler, Ramona, Schmitz, Andrea L., Plattet, Philippe, Zielinski, Jana, Mevissen, Meike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240602/ https://www.ncbi.nlm.nih.gov/pubmed/25415624 http://dx.doi.org/10.1371/journal.pone.0113540

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