α2β1 Integrin, GPVI Receptor, and Common FcRγ Chain on Mouse Platelets Mediate Distinct Responses to Collagen in Models of Thrombosis

OBJECTIVE: Platelets express the α2β1 integrin and the glycoprotein VI (GPVI)/FcRγ complex, both collagen receptors. Understanding platelet-collagen receptor function has been enhanced through use of genetically modified mouse models. Previous studies of GPVI/FcRγ-mediated collagen-induced platelet...

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Detalles Bibliográficos
Autores principales: Marjoram, Robin J., Li, Zhengzhi, He, Li, Tollefsen, Douglas M., Kunicki, Thomas J., Dickeson, S. Kent, Santoro, Samuel A., Zutter, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240667/
https://www.ncbi.nlm.nih.gov/pubmed/25415203
http://dx.doi.org/10.1371/journal.pone.0114035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240667/
https://www.ncbi.nlm.nih.gov/pubmed/25415203
http://dx.doi.org/10.1371/journal.pone.0114035

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