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Post-Injury Treatment with 7,8-Dihydroxyflavone, a TrkB Receptor Agonist, Protects against Experimental Traumatic Brain Injury via PI3K/Akt Signaling

Tropomyosin-related kinase B (TrkB) signaling is critical for promoting neuronal survival following brain damage. The present study investigated the effects and underlying mechanisms of TrkB activation by the TrkB agonist 7,8-dihydroxyflavone (7,8-DHF) on traumatic brain injury (TBI). Mice subjected...

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Detalles Bibliográficos
Autores principales:	Wu, Chun-Hu, Hung, Tai-Ho, Chen, Chien-Cheng, Ke, Chia-Hua, Lee, Chun-Yen, Wang, Pei-Yi, Chen, Szu-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240709/ https://www.ncbi.nlm.nih.gov/pubmed/25415296 http://dx.doi.org/10.1371/journal.pone.0113397

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