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TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus

BACKGROUND: Two-pore domain K(+) (K2P) channels have been shown to modulate neuronal excitability. However, physiological function of TWIK-1, the first identified member of the mammalian K2P channel family, in neuronal cells is largely unknown. RESULTS: We found that TWIK-1 proteins were expressed a...

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Detalles Bibliográficos
Autores principales: Yarishkin, Oleg, Lee, Da Yong, Kim, Eunju, Cho, Chang-Hoon, Choi, Jae Hyouk, Lee, C Justin, Hwang, Eun Mi, Park, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240835/
https://www.ncbi.nlm.nih.gov/pubmed/25406588
http://dx.doi.org/10.1186/s13041-014-0080-z