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E7080 (Lenvatinib), a Multi-Targeted Tyrosine Kinase Inhibitor, Demonstrates Antitumor Activities Against Colorectal Cancer Xenografts

Clinical prognosis of metastasized colorectal carcinoma (CRC) is still not at desired levels and novel drugs are needed. Here, we focused on the multi-tyrosine kinase inhibitor E7080 (Lenvatinib) and assessed its therapeutic efficacy against human CRC cell lines in vitro and human CRC xenografts in...

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Detalles Bibliográficos
Autores principales:	Wiegering, Armin, Korb, Doreen, Thalheimer, Andreas, Kämmerer, Ulrike, Allmanritter, Jan, Matthes, Niels, Linnebacher, Michael, Schlegel, Nicolas, Klein, Ingo, Ergün, Süleyman, Germer, Christoph-Thomas, Otto, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240916/ https://www.ncbi.nlm.nih.gov/pubmed/25425971 http://dx.doi.org/10.1016/j.neo.2014.09.008

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